Folate (As Metafolin®) 400µg 50 Tablets vs Active Folic 60 Capsules

Q: Which is better, Folate (As Metafolin®) 400µg 50 Tablets or Active Folic 60 Capsules?

Folate (As Metafolin®) 400µg 50 Tablets scores 86.0/100 while Active Folic 60 Capsules scores 80.0/100 in our analysis. Folate (As Metafolin®) 400µg 50 Tablets is the higher-rated product overall.

Q: Is Folate (As Metafolin®) 400µg 50 Tablets worth the price compared to Active Folic 60 Capsules?

Folate (As Metafolin®) 400µg 50 Tablets scores 68.0/100 for value, while Active Folic 60 Capsules scores 80.0/100. Check our price comparison above for the latest UK prices.

Side-by-side comparison of scores, ingredients, prices and real customer feedback for Folate (As Metafolin®) 400µg 50 Tablets and Active Folic 60 Capsules.

Last verified: 07 Apr 2026 · Based on 62 reviews

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86.0

Quick Answer

Folate (As Metafolin®) 400µg 50 Tablets scores 86.0/100 vs Active Folic 60 Capsules at 80.0/100. Folate (As Metafolin®) 400µg 50 Tablets wins on effectiveness, ingredient quality, side effects. Active Folic 60 Capsules is stronger on value for money.

How Do the Scores Compare?

Folate (As Metafolin®) 400µ...

Active Folic 60 Capsules

	Folate (As Metafolin®) 400µ... Solgar	Active Folic 60 Capsules Active Iron
Overall Score	86.0	80.0
Effectiveness	88.0/100 Best	80.0/100
Ingredient Quality	93.0/100 Best	80.0/100
Value for Money	68.0/100	80.0/100 Best
Side Effects	95.0/100 Best	90.0/100
Certifications	76.0/100 Best	40.0/100
Best Price	£9.20 Holland & Barrett → Cheapest	£12.99 Holland & Barrett →
Form	Tablets	capsule
Dose	None	None
Third-Party Tested	✗ No	✗ No
Reviews Analysed	58	4

Folate (As Metafolin®) 400µg 50 Tablets

Pros

✓Uses Metafolin® (L-5-methyltetrahydrofolate), the bioactive form directly usable by the body — superior absorption vs. synthetic folic acid
✓Highly effective for MTHFR mutation carriers who cannot convert regular folic acid
✓Multiple reviewers report confirmed improvements in blood folate levels via lab testing
✓Small, easy-to-swallow tablets with neutral taste and no reported digestive side effects

Cons

✗Small pack size — 50 tablets is only ~7 weeks' supply at the standard one-per-day dose
✗Not third-party tested per product specs, limiting independent purity verification
✗One Amazon reviewer reported receiving 46 tablets instead of 50 (possible quality control lapse)
✗Several iHerb reviews appear to describe the 1000mcg/120-tablet variant rather than this 400µg/50-tablet product, slightly muddying the review signal

Best For

Women planning pregnancy or currently pregnant MTHFR mutation carriers who cannot efficiently convert synthetic folic acid People with diagnosed folate deficiency Those seeking a clean, minimal-additive B-vitamin supplement Anyone wanting a well-trusted, established supplement brand

Holland & Barrett £9.20 Amazon UK £16.94

View full review →

Active Folic 60 Capsules

Pros

✓Methylfolate form (Quatrefolic®) offers superior bioavailability compared to synthetic folic acid
✓400μg dose meets UK and international preconception/pregnancy supplementation guidelines
✓Consistently praised by reviewers for gentle GI tolerability and ease of swallowing
✓Established brand (Active Iron) with positive reputation for quality supplements

Cons

✗No third-party testing certification mentioned (USP, NSF, etc.)
✗Not vegan (capsule and processing may contain animal-derived ingredients)
✗Only 4 reviews available—limited user feedback pool
✗No clinical data provided comparing actual absorption rates to standard folic acid claims

Best For

Women planning pregnancy or in early pregnancy Those with MTHFR gene variations who may benefit from methylfolate People seeking bioavailable folate without synthetic folic acid Users sensitive to standard supplements with good GI tolerance

Holland & Barrett £12.99

View full review →

What does the data say about Folate (As Metafolin®)... vs Active Folic 60 Capsules?

Folate (As Metafolin®) 400µg 50 Tablets from Solgar scores 86.0/100 overall and uses Metafolin which is the bioactive L-5-methyltetrahydrofolate form that the body can use straight away. Active Folic 60 Capsules from Active Iron scores 80.0/100 and relies on Quatrefolic methylfolate instead. Both deliver 400μg yet one comes as tablets while the other arrives in capsules. Solgar packs just 50 tablets so it lasts around seven weeks at one per day. Active Iron gives 60 capsules for a bit longer supply.

Solgar wins on effectiveness at 88.0/100 against 80.0/100 and on ingredient quality at 93.0/100 versus 80.0/100 so it suits MTHFR mutation carriers who cannot convert synthetic folic acid plus anyone with diagnosed folate deficiency. Active Folic wins on value at 80.0/100 compared with Solgar's 68.0/100 and costs £12.99 against Solgar's £9.20 which makes it the better pick for those on tighter budgets who still want methylfolate. People who need confirmed blood folate improvements from lab tests should choose Solgar. Those who rate gentle GI tolerability higher will prefer Active Folic.

Solgar tablets have no reported taste issues while Active Folic capsules earn praise for easy swallowing. Active Folic is not vegan because the capsule and processing may contain animal-derived ingredients. Solgar shows no such restriction in the details.

Folate (As Metafolin®) 400µg 50 Tablets Winner 86.0/100

Solgar's Folate as Metafolin® 400µg is a premium-grade folate supplement using L-methylfolate, the bioidentical, body-ready form of vitamin B9 that bypasses the need for hepatic conversion.

Effectiveness

Folate (As Metaf..

88.0/100

Active Folic 60 ..

80.0/100

Ingredient Quality

Folate (As Metaf..

93.0/100

Active Folic 60 ..

80.0/100

Value for Money

Folate (As Metaf..

68.0/100

Active Folic 60 ..

80.0/100

Side Effects

Folate (As Metaf..

95.0/100

Active Folic 60 ..

90.0/100

Certifications

Folate (As Metaf..

76.0/100

Active Folic 60 ..

40.0/100

What are the key differences?

Folate (As Metafolin®) .. is best for: Women planning pregnancy or currently pregnant, MTHFR mutation carriers who cannot efficiently convert synthetic folic acid

Active Folic 60 Capsules is best for: Women planning pregnancy or in early pregnancy, Those with MTHFR gene variations who may benefit from methylfolate

Frequently Asked Questions

Which is better, Folate (As Metafolin®) 400µg 50 Tablets or Active Folic 60 Capsules? ▼

Folate (As Metafolin®) 400µg 50 Tablets scores 86.0/100 overall while Active Folic 60 Capsules scores 80.0/100. Folate (As Metafolin®) 400µg 50 Tablets comes out ahead, scoring higher on effectiveness (88.0 vs 80.0). Folate (As Metafolin®) 400µg 5 is best suited for Women planning pregnancy or currently pregnant and MTHFR mutation carriers who cannot efficiently convert synthetic folic acid. Active Folic 60 Capsules is better for Women planning pregnancy or in early pregnancy and Those with MTHFR gene variations who may benefit from methylfolate.

Is Folate (As Metafolin®) 400µg 50 Tablets worth the price compared to Active Folic 60 Capsules? ▼

Folate (As Metafolin®) 400µg 50 Tablets costs £9.20 while Active Folic 60 Capsules is £12.99. For value, Folate (As Metafolin®) 400µg 50 Tablets scores 68.0/100 vs Active Folic 60 Capsules's 80.0/100. Active Folic 60 Capsules delivers better value relative to its quality. Note that Folate (As Metafolin comes as tablets while Active Folic 60 Capsules is capsule, which may affect your preference.

Which has fewer side effects? ▼

Folate (As Metafolin®) 400µg 50 Tablets scores 95.0/100 for side effects (higher means fewer reported issues) while Active Folic 60 Capsules scores 90.0/100. Reviewers report fewer side effects with Folate (As Metafolin®) 400µg 50 Tablets. For certification and testing, Folate (As Metafolin scores 76.0/100 vs Active Folic 60 Capsules's 40.0/100. Always consult a healthcare professional before starting any supplement.