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Folate (As Metafolin) 1000µg 60 Tablets vs B-Complex Plus

Side-by-side comparison of scores, ingredients, prices and real customer feedback for Folate (As Metafolin) 1000µg 60 Tablets and B-Complex Plus.

Last verified: 07 Apr 2026 · Based on 71 reviews

86.0
Quick Answer

Folate (As Metafolin) 1000µg 60 Tablets scores 86.0/100 vs B-Complex Plus at 77.0/100. Folate (As Metafolin) 1000µg 60 Tablets wins on effectiveness, ingredient quality, value for money. B-Complex Plus is stronger on certifications.

How Do the Scores Compare?

Folate (As Metafolin) 1000µ...
B-Complex Plus
Folate (As Metafolin) 1000µg 60 Tablets
Folate (As Metafolin) 1000µ...
Solgar
B-Complex Plus
B-Complex Plus
Thorne
Overall Score 86.0 77.0
Effectiveness 88.0/100
Best
74.0/100
Ingredient Quality 93.0/100
Best
91.0/100
Value for Money 73.0/100
Best
62.0/100
Side Effects 93.0/100
Best
81.0/100
Certifications 70.0/100 88.0/100
Best
Best Price £16.94 Amazon UK →
Cheapest
View →
Form Tablets N/A
Dose None N/A
Third-Party Tested ✗ No ✗ No
Reviews Analysed 57 14

Folate (As Metafolin) 1000µg 60 Tablets

Pros

  • Bioactive Metafolin® form (L-methylfolate) absorbed directly without MTHFR conversion — critical for MTHFR gene variant carriers
  • Multiple reviewers confirmed improved blood folate levels via lab tests, not just subjective feeling
  • Widely reported energy improvement and reduction in fatigue after consistent use
  • Clean ingredient profile — certified gluten-free, Kosher Parve, no artificial additives; packaged in glass bottle

Cons

  • Not third-party tested (e.g. NSF, Informed Sport) — relevant for those needing full verification
  • 1000mcg dose significantly exceeds the standard adult RDA (400mcg) and pregnancy recommendation (600mcg) — medical supervision advisable
  • Premium price point relative to standard folic acid alternatives; 60 tablets is a 2-month supply at 1/day
  • Isolated reports of tablets being difficult to swallow for some users

Best For

Women planning pregnancy or in early pregnancy People with confirmed MTHFR gene mutations (C677T, A1298C) Those with diagnosed folate deficiency or elevated homocysteine Anyone who hasn't responded well to standard folic acid supplementation Individuals on methotrexate or other medications that deplete folate People seeking a clean, additive-free premium folate supplement
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B-Complex Plus

Pros

  • Uses active, methylated B-vitamin forms for superior absorption and bioavailability
  • NSF Certified for Sport — independently tested for purity and label accuracy
  • Particularly effective for people with MTHFR mutations who cannot convert synthetic folate/B12
  • Clean formulation — minimal excipients, no unnecessary fillers or artificial colours

Cons

  • Premium price point — significantly more expensive than standard B-complex supplements
  • High-dose niacin (as niacinamide) may cause GI discomfort in sensitive individuals
  • Available review data for this exact product is sparse and partially from an unrelated company
  • Bright yellow urine from riboflavin is normal but can alarm first-time users

Best For

People with MTHFR gene variants Those with B12 absorption issues or on plant-based diets Athletes requiring NSF-certified supplements Adults with fatigue, stress, or cognitive fog Anyone prioritising ingredient form quality over cost
View full review →

What does the data say about Folate (As Metafolin) ... vs B-Complex Plus?

Folate (As Metafolin) 1000µg 60 Tablets from Solgar beats B-Complex Plus from Thorne with an overall score of 86.0/100 against 77.0/100. The main differences sit in their ingredient forms and focus. Solgar uses a single bioactive Metafolin form of folate at 1000µg per tablet while Thorne supplies a mix of active methylated B-vitamin forms including folate. Solgar comes as tablets with no listed dose frequency whereas Thorne offers no clear form or dose details in the data. Effectiveness scores show Solgar ahead at 88.0/100 compared with Thorne at 74.0/100 and ingredient quality sits close yet Solgar leads 93.0/100 to 91.0/100.

People with confirmed MTHFR gene mutations or diagnosed folate deficiency should pick Folate (As Metafolin) 1000µg 60 Tablets since it delivers direct absorption without conversion and users report better blood folate levels plus less fatigue after regular use. Those with B12 absorption issues or who follow plant-based diets will find B-Complex Plus from Thorne more suitable because it covers multiple B vitamins in methylated forms. Budget matters too. Solgar costs £16.94 and scores 73.0/100 on value while Thorne scores lower at 62.0/100 so it feels less attractive on price.

Practical points include the high 1000µg dose in Solgar which sits well above the usual 400mcg adult amount and may need medical advice. Thorne users sometimes mention stomach discomfort from the niacin content. No details appear on taste pill size or allergens for either product.

Folate (As Metafolin) 1000µg 60 Tablets Winner 86.0/100

Solgar's Folate as Metafolin 1000mcg delivers L-methylfolate (5-MTHF) via the patented Metafolin® form — the bioidentical, body-ready form of folate that bypasses the MTHFR enzyme conversion required by standard folic acid.

Effectiveness
Folate (As Metaf..
88.0/100
B-Complex Plus
74.0/100
Ingredient Quality
Folate (As Metaf..
93.0/100
B-Complex Plus
91.0/100
Value for Money
Folate (As Metaf..
73.0/100
B-Complex Plus
62.0/100
Side Effects
Folate (As Metaf..
93.0/100
B-Complex Plus
81.0/100
Certifications
Folate (As Metaf..
70.0/100
B-Complex Plus
88.0/100

What are the key differences?

Folate (As Metafolin) 1.. is best for: Women planning pregnancy or in early pregnancy, People with confirmed MTHFR gene mutations (C677T, A1298C)
B-Complex Plus is best for: People with MTHFR gene variants, Those with B12 absorption issues or on plant-based diets

Frequently Asked Questions

Which is better, Folate (As Metafolin) 1000µg 60 Tablets or B-Complex Plus?
Folate (As Metafolin) 1000µg 60 Tablets scores 86.0/100 overall while B-Complex Plus scores 77.0/100. Folate (As Metafolin) 1000µg 60 Tablets comes out ahead, scoring higher on effectiveness (88.0 vs 74.0). Folate (As Metafolin) 1000µg 6 is best suited for Women planning pregnancy or in early pregnancy and People with confirmed MTHFR gene mutations (C677T, A1298C). B-Complex Plus is better for People with MTHFR gene variants and Those with B12 absorption issues or on plant-based diets.
Is Folate (As Metafolin) 1000µg 60 Tablets worth the price compared to B-Complex Plus?
For value, Folate (As Metafolin) 1000µg 60 Tablets scores 73.0/100 vs B-Complex Plus's 62.0/100. Folate (As Metafolin) 1000µg 60 Tablets delivers better value relative to its quality.
Which has fewer side effects?
Folate (As Metafolin) 1000µg 60 Tablets scores 93.0/100 for side effects (higher means fewer reported issues) while B-Complex Plus scores 81.0/100. Reviewers report fewer side effects with Folate (As Metafolin) 1000µg 60 Tablets. For certification and testing, Folate (As Metafolin scores 70.0/100 vs B-Complex Plus's 88.0/100. Always consult a healthcare professional before starting any supplement.

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Disclaimer: AIScored provides data-driven comparisons based on publicly available reviews. This is not medical advice. Affiliate links may earn us a commission at no extra cost to you.

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