Dymatize ISO100 Hydrolyzed Whey Protein Isolate 2.2kg vs 50g High Protein Shake Vanilla 500ml
Side-by-side comparison of scores, ingredients, prices and real customer feedback for Dymatize ISO100 Hydrolyzed Whey Protein Isolate 2.2kg and 50g High Protein Shake Vanilla 500ml.
Last verified: 07 Apr 2026 · Based on 31 reviews
Dymatize ISO100 Hydrolyzed Whey Protein Isolate 2.2kg scores 84.0/100 vs 50g High Protein Shake Vanilla 500ml at 80.0/100. Dymatize ISO100 Hydrolyzed Whey Protein Isolate 2.2kg wins on effectiveness, ingredient quality, side effects. 50g High Protein Shake Vanilla 500ml is stronger on value for money.
Which is better: Dymatize ISO100 Hydrolyzed ... or 50g High Protein Shake Vani...?
Dymatize ISO100 wins with a higher score (84 vs 80) and superior ingredient quality (90 vs 70), making it the better pick for serious athletes who need certified clean, fast-absorbing protein. The ON Ready-to-Drink suits those wanting grab-and-go convenience at £3.25 per serving without committing to a bulk tub.
— AIScored Editorial Team
How Do the Scores Compare?
Dymatize ISO100 Hydrolyzed ...
Dymatize
|
50g High Protein Shake Vani...
Optimum Nutrition
|
|
|---|---|---|
| Overall Score | 84.0 | 80.0 |
| Effectiveness |
88.0/100
Best
|
80.0/100 |
| Ingredient Quality |
90.0/100
Best
|
70.0/100 |
| Value for Money | 68.0/100 |
70.0/100
Best
|
| Side Effects |
89.0/100
Best
|
80.0/100 |
| Certifications |
93.0/100
Best
|
30.0/100 |
| Best Price | £89.99 Amazon UK → |
£3.25
Holland & Barrett →
Cheapest
|
| Price per Serving | £1.30 69 servings | N/A |
| Form | Powder | None |
| Dose | 25g protein per 32g serving | None |
| Third-Party Tested | ✓ Yes | ✗ No |
| Reviews Analysed | 27 | 4 |
Dymatize ISO100 Hydrolyzed Whey ...
Pros
- ✓Excellent mixability — reviewers consistently note it blends smoothly without clumping or leaving a thick texture
- ✓Great taste across flavours — H&B reviewers praise it as genuinely enjoyable, not just tolerable
- ✓Hydrolyzed formula for faster absorption — ideal post-workout when rapid amino acid delivery matters
- ✓Very clean macros — 25g protein, <1g sugar, <1g fat, 120 kcal per serving with 5.5g BCAAs including 2.7g leucine (above MPS threshold)
Cons
- ✗Premium price point — explicitly flagged by reviewers and among the most expensive isolates per serving
- ✗Can be overly sweet at standard dilution — one reviewer recommends 450ml water per scoop rather than the suggested amount
- ✗Contains soy lecithin — minor concern for those avoiding soy entirely
- ✗Uses sucralose (artificial sweetener) alongside stevia — not suitable for those avoiding artificial additives
Best For
50g High Protein Shake Vanilla 500ml
Pros
- ✓Excellent taste (specifically vanilla flavor praised by multiple reviewers)
- ✓High protein content (50g per 500ml serving) meets user expectations
- ✓No added sugars formulation appeals to health-conscious consumers
- ✓Convenient ready-to-drink format for on-the-go protein
Cons
- ✗No third-party testing or certification for quality assurance
- ✗Not vegan-friendly (contains milk proteins)
- ✗Limited flavor variety mentioned (only 3 flavors available)
- ✗UHT processing may affect some perceptions of ingredient freshness
Best For
What does the data say about Dymatize ISO100 Hydrol... vs 50g High Protein Shake...?
Dymatize ISO100 is a hydrolyzed whey protein isolate in powder form, delivering 25g of protein per 32g serving — a format designed for mixing at home. The hydrolysis process pre-digests the whey, theoretically speeding up amino acid absorption post-workout, and the isolate processing removes virtually all lactose. It scores 90/100 for ingredient quality and carries third-party testing certification. The Optimum Nutrition shake is a ready-to-drink 500ml bottle with 50g protein — no scooping, no shaker required — though it scores lower on ingredient quality at 70/100 and has no third-party certification.
If you train seriously, care about certified clean protein, or are lactose-sensitive, the Dymatize at £89.99 for 2.2kg makes sense despite the premium — it works out reasonable per serving when bought in bulk. The ON shake at £3.25 suits anyone who wants protein on the go without any preparation, or who genuinely struggles to hit 50g protein in a single sitting.
Practically, the Dymatize can taste overly sweet — reviewers suggest 450ml water per scoop rather than the standard amount. The ON shake is dairy-based and unsuitable for vegans. If certifications matter to you, only the Dymatize delivers them.
Dymatize ISO100 is a premium hydrolyzed whey protein isolate that consistently earns strong praise from verified buyers for its taste, mixability, and clean macronutrient profile.
What are the key differences?
Frequently Asked Questions
Which is better, Dymatize ISO100 Hydrolyzed Whey Protein Isolate 2.2kg or 50g High Protein Shake Vanilla 500ml? ▼
Is Dymatize ISO100 Hydrolyzed Whey Protein Isolate 2.2kg worth the price compared to 50g High Protein Shake Vanilla 500ml? ▼
Which has fewer side effects? ▼
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What the Data Says
What makes a clean whey protein? Ingredient quality scores across 169 UK products
Fewer ingredients = cleaner protein. We scored 169 whey proteins on ingredient quality (IQ) and the gap between top and bottom is massive: 65 points, from 95/100 down to 30/100.
The top 7 products by IQ all share one trait — minimal ingredient lists:
- PINK SUN Organic Whey Concentrate — IQ 95, overall 85
- Isopure Unflavoured Whey Isolate — IQ 91, overall 76
- LEGION Whey+ Isolate — IQ 91, overall 80
- PINK SUN Whey Isolate Unflavoured — IQ 91, overall 81
- Purition 100% Whey Isolate 93% Protein — IQ 91, overall 80
- Dymatize ISO100 — IQ 90, overall 84
- Naked Whey (1 ingredient) — IQ 90, overall 74
The bottom tells the opposite story. Products like BodyFuel Clear Protein (IQ 30), Amfit Nutrition (IQ 38), and Protein Dynamix 3XP (IQ 38) use multi-source protein blends padded with artificial sweeteners, thickeners, and colourings.
The average across all 169 products is 70.7/100. If your whey protein has more than 5-6 ingredients, check what's filling up that list. A clean whey needs protein, maybe a natural flavour, and not much else.
Can cheap whey protein cause bloating? What to check on the label
Cheap whey often causes bloating because of what's added to the protein, not the protein itself. We scored 169 whey proteins and the worst-scoring products share the same filler-heavy ingredient profiles.
Three categories of additives show up repeatedly in low-IQ products (scored 30-42):
- Thickeners — xanthan gum, carrageenan, cellulose gum. These bulk up texture but can cause gas and bloating in sensitive stomachs.
- Artificial sweeteners — sucralose, acesulfame-K, aspartame. Linked to gut microbiome disruption in some studies. Budget brands use these heavily.
- Anti-caking agents and emulsifiers — added to improve mixability, but another source of digestive irritation.
Products like BodyFuel Clear Protein (IQ 30), Amfit Nutrition (IQ 38), and SCI-MX Ultra Muscle (IQ 42) stack several of these additives together.
Compare that to the top scorers: PINK SUN Organic Whey (IQ 95) and Naked Whey (IQ 90) use 1-3 ingredients total. No thickeners, no artificial sweeteners, no fillers. Users report far less digestive trouble with these minimal formulas.
Label check shortcut: flip the tub over. If the ingredient list has more than 6 items, or you spot carrageenan, sucralose, or acesulfame-K, that's your likely bloating culprit. A whey isolate with a short list costs a bit more but your gut will thank you.
Disclaimer: AIScored provides data-driven comparisons based on publicly available reviews. This is not medical advice. Affiliate links may earn us a commission at no extra cost to you.
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