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Zinc Picolinate 22mg vs Igennus Clean Chelated Zinc Picolinate & Bisglycinate Complex 25mg with Copper, 6 Month Supply 180 Tablets, High Absorption & Lab Verified, Non-GMO, Supplement for Men & Women, Immune Support & Skin

Side-by-side comparison of scores, ingredients, prices and real customer feedback for Zinc Picolinate 22mg and Igennus Clean Chelated Zinc Picolinate & Bisglycinate Complex 25mg with Copper, 6 Month Supply 180 Tablets, High Absorption & Lab Verified, Non-GMO, Supplement for Men & Women, Immune Support & Skin.

Last verified: 07 Apr 2026 · Based on 76 reviews

85.0
Quick Answer

Zinc Picolinate 22mg scores 85.0/100 vs Igennus Clean Chelated Zinc Picolinate & Bisglycinate Complex 25mg with Copper, 6 Month Supply 180 Tablets, High Absorption & Lab Verified, Non-GMO, Supplement for Men & Women, Immune Support & Skin at 81.0/100. Zinc Picolinate 22mg wins on effectiveness, ingredient quality, certifications. Igennus Clean Chelated Zinc Picolinate & Bisglycinate Complex 25mg with Copper, 6 Month Supply 180 Tablets, High Absorption & Lab Verified, Non-GMO, Supplement for Men & Women, Immune Support & Skin is stronger on value for money and side effects.

Which is better: Zinc Picolinate 22mg or Igennus Clean Chelated Zinc...?

Thorne wins on effectiveness (84/100 vs 76/100) and ingredient quality (91 vs 88), with an overall score of 85/100. Pick Igennus instead if budget is key: it costs £6.43 less, includes copper to prevent depletion, and offers superior tolerability even on an empty stomach.

— AIScored Editorial Team

How Do the Scores Compare?

Zinc Picolinate 22mg
Igennus Clean Chelated Zinc...
Zinc Picolinate 22mg
Zinc Picolinate 22mg
Thorne
Igennus Clean Chelated Zinc Picolinate & Bisglycinate Complex 25mg with Copper, 6 Month Supply 180 Tablets, High Absorption & Lab Verified, Non-GMO, Supplement for Men & Women, Immune Support & Skin
Igennus Clean Chelated Zinc...
Igennus Healthcare Nutrition
Overall Score 85.0 81.0
Effectiveness 84.0/100
Best
76.0/100
Ingredient Quality 91.0/100
Best
88.0/100
Value for Money 74.0/100 83.0/100
Best
Side Effects 86.0/100 91.0/100
Best
Certifications 89.0/100
Best
70.0/100
Best Price £21.38 Amazon UK → £14.95 Amazon UK →
Cheapest
Form N/A ‎Tablet
Dose N/A None
Third-Party Tested ✗ No ✗ No
Reviews Analysed 63 13

Zinc Picolinate 22mg

Pros

  • Zinc picolinate is among the most bioavailable zinc forms — well absorbed even with reduced stomach acidity
  • Thorne Research brand known for rigorous purity testing, NSF certification, and minimal excipients
  • Widely reported benefits: reduced hair loss, clearer skin, stronger nails, fewer colds
  • Small capsules, neutral taste, no significant aftertaste — easy to incorporate daily

Cons

  • Mild nausea possible if taken on an empty stomach — best taken with food
  • Long-term use requires copper supplementation to prevent copper depletion
  • Premium brand pricing — higher cost per serving than budget zinc options
  • Dosage (15–22mg) may be insufficient for therapeutic use in severe deficiency without medical guidance

Best For

Those with zinc deficiency symptoms (hair loss, brittle nails, frequent colds) People with sensitive stomachs who struggle with other zinc forms Men supporting testosterone and reproductive health Women managing hormonal balance or preparing for pregnancy Anyone seeking a clean, certified supplement with no unnecessary additives
View full review →

Igennus Clean Chelated Zinc Pico...

Pros

  • Highly tolerated — multiple reviewers explicitly note no nausea or stomach upset, even when taken on an empty stomach
  • Copper bisglycinate included at a balanced ratio, preventing zinc-induced copper depletion for safe long-term use
  • Dual chelated forms (picolinate + bisglycinate) offer superior absorption over cheaper gluconate or oxide forms
  • Clean, verifiable formula — no magnesium stearate, titanium dioxide, artificial colours, or fillers; UK GMP-manufactured

Cons

  • Not effective for all conditions — one reviewer saw no benefit for gastritis, and zinc's evidence for gut inflammation is limited
  • Effects take time to assess; short-term users (under 2–4 weeks) cannot judge efficacy reliably
  • Third-party testing not independently confirmed despite 'lab verified' marketing claim
  • Tablet form may not suit those preferring capsules or liquids

Best For

Athletes and high-stress individuals with elevated zinc turnover Post-surgical patients supporting wound healing People with zinc-responsive skin conditions (acne, HS, dermatitis) Anyone who has experienced nausea or GI upset with standard zinc supplements Long-term supplementers who need copper co-supplementation built in Vegan and halal/kosher dietary requirements
View full review →

What does the data say about Zinc Picolinate 22mg vs Igennus Clean Chelated...?

Both products use zinc picolinate as their base form, which is among the better-absorbed options compared to cheaper oxide or gluconate. The key difference is that Igennus adds zinc bisglycinate alongside the picolinate, plus includes copper bisglycinate in the formula itself — meaning you get a dual-chelated complex in one tablet. Thorne's offering is a single-form zinc without copper, so you'd need to supplement copper separately if using it long-term. Thorne scores higher overall at 85/100 versus Igennus's 81/100, but Igennus edges ahead on value at 83/100 compared to Thorne's 74/100 — and at £14.95 for 180 tablets, the price difference is substantial against Thorne's £21.38.

If you want the simplest, highest-quality single-ingredient zinc and don't mind managing copper separately, Thorne is the cleaner choice — particularly if you're already taking a multi that includes copper. Its ingredient quality score of 91/100 reflects Thorne's well-regarded manufacturing standards.

For most people, though, Igennus makes more practical sense. The built-in copper removes the need for an extra supplement, stomach tolerance appears better across reviewers, and the six-month supply format suits anyone looking to commit to consistent long-term use without frequent reorders.

Zinc Picolinate 22mg Winner 85.0/100

Thorne Zinc Picolinate is a well-regarded supplement using zinc picolinate, one of the most bioavailable forms of zinc, bound to picolinic acid for superior absorption even in low-stomach-acid conditions.

Effectiveness
Zinc Picolinate 22mg
84.0/100
Igennus Clean Ch..
76.0/100
Ingredient Quality
Zinc Picolinate 22mg
91.0/100
Igennus Clean Ch..
88.0/100
Value for Money
Zinc Picolinate 22mg
74.0/100
Igennus Clean Ch..
83.0/100
Side Effects
Zinc Picolinate 22mg
86.0/100
Igennus Clean Ch..
91.0/100
Certifications
Zinc Picolinate 22mg
89.0/100
Igennus Clean Ch..
70.0/100

What are the key differences?

Zinc Picolinate 22mg is best for: Those with zinc deficiency symptoms (hair loss, brittle nails, frequent colds), People with sensitive stomachs who struggle with other zinc forms
Igennus Clean Chelated .. is best for: Athletes and high-stress individuals with elevated zinc turnover, Post-surgical patients supporting wound healing

Frequently Asked Questions

Which is better, Zinc Picolinate 22mg or Igennus Clean Chelated Zinc Picolinate & Bisglycinate Complex 25mg with Copper, 6 Month Supply 180 Tablets, High Absorption & Lab Verified, Non-GMO, Supplement for Men & Women, Immune Support & Skin?
Zinc Picolinate 22mg scores 85.0/100 overall while Igennus Clean Chelated Zinc Picolinate & Bisglycinate Complex 25mg with Copper, 6 Month Supply 180 Tablets, High Absorption & Lab Verified, Non-GMO, Supplement for Men & Women, Immune Support & Skin scores 81.0/100. Zinc Picolinate 22mg comes out ahead, scoring higher on effectiveness (84.0 vs 76.0). Zinc Picolinate 22mg is best suited for Those with zinc deficiency symptoms (hair loss, brittle nails, frequent colds) and People with sensitive stomachs who struggle with other zinc forms. Igennus Clean Chelated Zinc Pi is better for Athletes and high-stress individuals with elevated zinc turnover and Post-surgical patients supporting wound healing.
Is Zinc Picolinate 22mg worth the price compared to Igennus Clean Chelated Zinc Picolinate & Bisglycinate Complex 25mg with Copper, 6 Month Supply 180 Tablets, High Absorption & Lab Verified, Non-GMO, Supplement for Men & Women, Immune Support & Skin?
Zinc Picolinate 22mg costs £21.38 while Igennus Clean Chelated Zinc Picolinate & Bisglycinate Complex 25mg with Copper, 6 Month Supply 180 Tablets, High Absorption & Lab Verified, Non-GMO, Supplement for Men & Women, Immune Support & Skin is £14.95. For value, Zinc Picolinate 22mg scores 74.0/100 vs Igennus Clean Chelated Zinc Picolinate & Bisglycinate Complex 25mg with Copper, 6 Month Supply 180 Tablets, High Absorption & Lab Verified, Non-GMO, Supplement for Men & Women, Immune Support & Skin's 83.0/100. Igennus Clean Chelated Zinc Picolinate & Bisglycinate Complex 25mg with Copper, 6 Month Supply 180 Tablets, High Absorption & Lab Verified, Non-GMO, Supplement for Men & Women, Immune Support & Skin delivers better value relative to its quality.
Which has fewer side effects?
Zinc Picolinate 22mg scores 86.0/100 for side effects (higher means fewer reported issues) while Igennus Clean Chelated Zinc Picolinate & Bisglycinate Complex 25mg with Copper, 6 Month Supply 180 Tablets, High Absorption & Lab Verified, Non-GMO, Supplement for Men & Women, Immune Support & Skin scores 91.0/100. Reviewers report fewer side effects with Igennus Clean Chelated Zinc Picolinate & Bisglycinate Complex 25mg with Copper, 6 Month Supply 180 Tablets, High Absorption & Lab Verified, Non-GMO, Supplement for Men & Women, Immune Support & Skin. For certification and testing, Zinc Picolinate 22mg scores 89.0/100 vs Igennus Clean Chelat's 70.0/100. Always consult a healthcare professional before starting any supplement.

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