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Life Extension Neuro-Mag Magnesium L-Threonate vs Nutravita Magnesium Supplements 5-in-1 Complex 1146mg - Which? Best Buy 2025-240 High Strength Capsules - 400mg Elemental Magnesium: Bisglycinate, Citrate, Malate, Oxide, Ascorbate - Muscles & Sleep

Side-by-side comparison of scores, ingredients, prices and real customer feedback for Life Extension Neuro-Mag Magnesium L-Threonate and Nutravita Magnesium Supplements 5-in-1 Complex 1146mg - Which? Best Buy 2025-240 High Strength Capsules - 400mg Elemental Magnesium: Bisglycinate, Citrate, Malate, Oxide, Ascorbate - Muscles & Sleep.

Last verified: 07 Apr 2026 · Based on 78 reviews

73.0
Quick Answer

Life Extension Neuro-Mag Magnesium L-Threonate scores 73.0/100 vs Nutravita Magnesium Supplements 5-in-1 Complex 1146mg - Which? Best Buy 2025-240 High Strength Capsules - 400mg Elemental Magnesium: Bisglycinate, Citrate, Malate, Oxide, Ascorbate - Muscles & Sleep at 73.0/100. Life Extension Neuro-Mag Magnesium L-Threonate wins on effectiveness, ingredient quality, certifications. Nutravita Magnesium Supplements 5-in-1 Complex 1146mg - Which? Best Buy 2025-240 High Strength Capsules - 400mg Elemental Magnesium: Bisglycinate, Citrate, Malate, Oxide, Ascorbate - Muscles & Sleep is stronger on value for money and side effects.

How Do the Scores Compare?

Life Extension Neuro-Mag Ma...
Nutravita Magnesium Supplem...
Life Extension Neuro-Mag Magnesium L-Threonate
Life Extension Neuro-Mag Ma...
Life Extension
Nutravita Magnesium Supplements 5-in-1 Complex 1146mg - Which? Best Buy 2025-240 High Strength Capsules - 400mg Elemental Magnesium: Bisglycinate, Citrate, Malate, Oxide, Ascorbate - Muscles & Sleep
Nutravita Magnesium Supplem...
Nutravita
Overall Score 73.0 73.0
Effectiveness 73.0/100
Best
72.0/100
Ingredient Quality 86.0/100
Best
64.0/100
Value for Money 52.0/100 82.0/100
Best
Side Effects 76.0/100 85.0/100
Best
Certifications 80.0/100
Best
68.0/100
Best Price £37.90 Amazon UK → £15.99 Amazon UK →
Cheapest
Price per Serving £1.26 30 servings
Best value
£15.99 1 servings
Form Capsules Capsule
Dose 2000mg Magtein (144mg elemental Mg) None
Third-Party Tested ✓ Yes ✗ No
Reviews Analysed 68 10

Life Extension Neuro-Mag Magnesi...

Pros

  • Magtein (patented Mg L-threonate) is the most researched form for crossing the blood-brain barrier and supporting cognitive function
  • Reviewers consistently report improved memory, concentration, and reduced brain fog after several weeks of use
  • Sleep quality improvements frequently mentioned — easier to fall asleep, fewer nighttime awakenings
  • Clean formula: vegan capsules, no dairy, gluten, soy, or artificial flavours; third-party tested

Cons

  • Premium pricing with only 30 servings per bottle makes ongoing use costly compared to standard magnesium forms
  • High capsule load (3 per serving) due to low elemental magnesium yield of the L-threonate form
  • Some users report vivid dreams or mild sleep disruption, especially if taken close to bedtime
  • Effects are gradual — requires 2–4 weeks of consistent use before benefits are noticeable

Best For

Adults seeking targeted cognitive and memory support Students or knowledge workers with high mental demand Over 50s concerned about age-related memory changes People with poor sleep quality linked to low magnesium Those who have experienced digestive issues with other magnesium forms
View full review →

Nutravita Magnesium Supplements ...

Pros

  • Multiple reviewers report genuine improvements in night-time muscle cramps and sleep depth
  • 400mg elemental magnesium is a full therapeutic dose — not token amounts
  • Includes bisglycinate and citrate, two of the best-absorbed forms available
  • Which? Best Buy 2025 rating and UK GMP/BRC manufacturing standards

Cons

  • Magnesium oxide is the lowest-bioavailability form (~4%) and pads the blend without proportional benefit
  • Per-form ratios are not disclosed — you cannot tell how much bisglycinate versus oxide you're actually getting
  • Not independently third-party tested; GMP/BRC covers manufacturing process, not label accuracy
  • One reviewer explicitly notes this is a suboptimal choice if sleep is the primary goal — glycinate or L-threonate alone may work better

Best For

People wanting broad daily magnesium cover — muscles, nerve function, energy — rather than a targeted single-form protocol Those experiencing muscle cramps or night-time leg restlessness, where the citrate and bisglycinate fractions should help Budget-conscious buyers who want multiple premium forms without buying four separate products
View full review →

What does the data say about Life Extension Neuro-M... vs Nutravita Magnesium Su...?

Life Extension Neuro-Mag Magnesium L-Threonate Winner 73.0/100

Life Extension Neuro-Mag Magnesium L-Threonate uses Magtein, the patented and clinically studied form of magnesium L-threonate developed specifically to cross the blood-brain barrier and support synaptic density.

Effectiveness
Life Extension N..
73.0/100
Nutravita Magnes..
72.0/100
Ingredient Quality
Life Extension N..
86.0/100
Nutravita Magnes..
64.0/100
Value for Money
Life Extension N..
52.0/100
Nutravita Magnes..
82.0/100
Side Effects
Life Extension N..
76.0/100
Nutravita Magnes..
85.0/100
Certifications
Life Extension N..
80.0/100
Nutravita Magnes..
68.0/100

What are the key differences?

Life Extension Neuro-Ma.. is best for: Adults seeking targeted cognitive and memory support, Students or knowledge workers with high mental demand
Nutravita Magnesium Sup.. is best for: People wanting broad daily magnesium cover — muscles, nerve function, energy — rather than a targeted single-form protocol, Those experiencing muscle cramps or night-time leg restlessness, where the citrate and bisglycinate fractions should help

Frequently Asked Questions

Which is better, Life Extension Neuro-Mag Magnesium L-Threonate or Nutravita Magnesium Supplements 5-in-1 Complex 1146mg - Which? Best Buy 2025-240 High Strength Capsules - 400mg Elemental Magnesium: Bisglycinate, Citrate, Malate, Oxide, Ascorbate - Muscles & Sleep?
Life Extension Neuro-Mag Magnesium L-Threonate scores 73.0/100 overall while Nutravita Magnesium Supplements 5-in-1 Complex 1146mg - Which? Best Buy 2025-240 High Strength Capsules - 400mg Elemental Magnesium: Bisglycinate, Citrate, Malate, Oxide, Ascorbate - Muscles & Sleep scores 73.0/100. Both score equally overall — the difference comes down to individual dimensions. Life Extension Neuro-Mag Magne is best suited for Adults seeking targeted cognitive and memory support and Students or knowledge workers with high mental demand. Nutravita Magnesium Supplement is better for People wanting broad daily magnesium cover — muscles, nerve function, energy — rather than a targeted single-form protocol and Those experiencing muscle cramps or night-time leg restlessness, where the citrate and bisglycinate fractions should help.
Is Life Extension Neuro-Mag Magnesium L-Threonate worth the price compared to Nutravita Magnesium Supplements 5-in-1 Complex 1146mg - Which? Best Buy 2025-240 High Strength Capsules - 400mg Elemental Magnesium: Bisglycinate, Citrate, Malate, Oxide, Ascorbate - Muscles & Sleep?
Life Extension Neuro-Mag Magnesium L-Threonate costs £37.90 while Nutravita Magnesium Supplements 5-in-1 Complex 1146mg - Which? Best Buy 2025-240 High Strength Capsules - 400mg Elemental Magnesium: Bisglycinate, Citrate, Malate, Oxide, Ascorbate - Muscles & Sleep is £15.99. For value, Life Extension Neuro-Mag Magnesium L-Threonate scores 52.0/100 vs Nutravita Magnesium Supplements 5-in-1 Complex 1146mg - Which? Best Buy 2025-240 High Strength Capsules - 400mg Elemental Magnesium: Bisglycinate, Citrate, Malate, Oxide, Ascorbate - Muscles & Sleep's 82.0/100. Nutravita Magnesium Supplements 5-in-1 Complex 1146mg - Which? Best Buy 2025-240 High Strength Capsules - 400mg Elemental Magnesium: Bisglycinate, Citrate, Malate, Oxide, Ascorbate - Muscles & Sleep delivers better value relative to its quality. Note that Life Extension Neuro comes as capsules while Nutravita Magnesium is capsule, which may affect your preference.
Which has fewer side effects?
Life Extension Neuro-Mag Magnesium L-Threonate scores 76.0/100 for side effects (higher means fewer reported issues) while Nutravita Magnesium Supplements 5-in-1 Complex 1146mg - Which? Best Buy 2025-240 High Strength Capsules - 400mg Elemental Magnesium: Bisglycinate, Citrate, Malate, Oxide, Ascorbate - Muscles & Sleep scores 85.0/100. Reviewers report fewer side effects with Nutravita Magnesium Supplements 5-in-1 Complex 1146mg - Which? Best Buy 2025-240 High Strength Capsules - 400mg Elemental Magnesium: Bisglycinate, Citrate, Malate, Oxide, Ascorbate - Muscles & Sleep. For certification and testing, Life Extension Neuro scores 80.0/100 vs Nutravita Magnesium 's 68.0/100. Always consult a healthcare professional before starting any supplement.

Related Product Comparisons

What the Data Says

Why is magnesium oxide less effective than glycinate?

Oxide scores 21 points lower than glycinate in our testing — and it's not close on ingredient quality either. Across 17 magnesium products in our database, glycinate averages 74.3/100 overall. Oxide sits at 53/100. That's a gap you can feel.

The ingredient quality difference is even starker: 83.3 for glycinate vs 37.0 for oxide. A 46.3-point gap. The best glycinate in our database, Solgar Magnesium Glycinate 400mg, scores 80/100 overall with 88/100 on ingredient quality. The oxide product (Nature Made) manages just 52 on effectiveness and 37 on ingredient quality.

The reason is bioavailability. Magnesium oxide has roughly 4% absorption — most of it passes straight through your gut unused. Glycinate is chelated (bound to the amino acid glycine), which your intestines absorb much more efficiently. You also get fewer digestive side effects, since unabsorbed magnesium in the gut is what causes the laxative effect oxide is known for.

Oxide is cheap, which is why it's still everywhere. But cheap per pill means nothing if your body can't use it. Glycinate or citrate (avg 74.5/100) are both better choices.

Which form of magnesium is best for sleep, anxiety, or muscle cramps?

Glycinate for sleep and anxiety. Citrate for cramps. L-threonate for brain function. Each form has a different strength, and our scores back this up.

Sleep and anxiety → Glycinate. Averaging 74.3/100 across our database, with the best (Solgar Glycinate 400mg) hitting 80/100. Glycine, the amino acid it's bound to, acts as an inhibitory neurotransmitter — it calms your nervous system on its own. That's a two-for-one benefit you don't get from other forms. Thorne Bisglycinate (74/100) is another solid option at a lower dose.

Muscle cramps → Citrate. Averaging 74.5/100 overall with 85.0 on ingredient quality. Citrate absorbs well and is gentler on your wallet than glycinate. Solgar Citrate leads the pack at 77/100. If cramps are your main issue, this is the practical choice.

Brain function → L-Threonate. Life Extension Neuro-Mag scores 73/100. This is the only form shown to meaningfully raise magnesium levels in the brain by crossing the blood-brain barrier. It's pricier, but nothing else does what it does.

All-round absorption → Doctor's Best High Absorption tops our entire magnesium database at 82/100 overall (83 effectiveness, 88 ingredient quality) using chelated magnesium.

The one form to skip? Oxide at 53/100. Its 4% absorption rate makes it a poor choice no matter what you're taking it for.

Disclaimer: AIScored provides data-driven comparisons based on publicly available reviews. This is not medical advice. Affiliate links may earn us a commission at no extra cost to you.

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