Life Extension Super Omega-3 EPA/DHA Fish Oil vs NOW Foods Ultra Omega-3 500 EPA / 250 DHA
Side-by-side comparison of scores, ingredients, prices and real customer feedback for Life Extension Super Omega-3 EPA/DHA Fish Oil and NOW Foods Ultra Omega-3 500 EPA / 250 DHA.
Last verified: 07 Apr 2026 · Based on 121 reviews
Life Extension Super Omega-3 EPA/DHA Fish Oil scores 86.0/100 vs NOW Foods Ultra Omega-3 500 EPA / 250 DHA at 83.0/100. Life Extension Super Omega-3 EPA/DHA Fish Oil wins on effectiveness, ingredient quality, side effects. NOW Foods Ultra Omega-3 500 EPA / 250 DHA is stronger on value for money.
Which is better: Life Extension Super Omega-... or NOW Foods Ultra Omega-3 500...?
Life Extension edges ahead with an 86 vs 83 score, thanks to IFOS 5-star certification and a unique sesame lignan and olive polyphenol formula that extends anti-inflammatory benefit. NOW Foods is the better pick for anyone troubled by fishy aftertaste, as its enteric coating reliably solves that problem, and at £5 less it offers stronger value for a straightforward high-potency daily dose.
— AIScored Editorial Team
How Do the Scores Compare?
Life Extension Super Omega-...
Life Extension
|
NOW Foods Ultra Omega-3 500...
NOW Foods
|
|
|---|---|---|
| Overall Score | 86.0 | 83.0 |
| Effectiveness |
83.0/100
Best
|
82.0/100 |
| Ingredient Quality |
91.0/100
Best
|
79.0/100 |
| Value for Money | 80.0/100 |
85.0/100
Best
|
| Side Effects |
87.0/100
Best
|
83.0/100 |
| Certifications |
92.0/100
Best
|
88.0/100 |
| Best Price | £24.99 Amazon UK → |
£19.99
Amazon UK →
Cheapest
|
| Price per Serving | £0.42 60 servings |
£0.22
90 servings
Best value
|
| Form | Softgels | Softgels |
| Dose | 700mg EPA+DHA + sesame lignans + olive extract | 750mg EPA+DHA |
| Third-Party Tested | ✓ Yes | ✓ Yes |
| Reviews Analysed | 57 | 64 |
Life Extension Super Omega-3 EPA...
Pros
- ✓IFOS 5-star certified and molecularly distilled — among the highest purity standards available for fish oil
- ✓Unique synergistic formula: sesame lignans and olive polyphenols (hydroxytyrosol) extend omega-3 anti-inflammatory activity beyond standard fish oil
- ✓Widely reported tangible benefits: improved cholesterol, reduced joint and systemic inflammation, better skin, hair, and nails
- ✓Minimal fishy aftertaste and good tolerability reported by the majority of reviewers
Cons
- ✗Softgels are noted as larger than average by multiple reviewers — may be difficult for those with swallowing issues
- ✗Omega form is not specified on labelling and is likely ethyl ester rather than triglyceride form, which has lower bioavailability
- ✗Contains sesame — a declared allergen increasingly relevant for sensitive individuals
- ✗Mild fish odour noted by a minority of reviewers, particularly after opening the capsule
Best For
NOW Foods Ultra Omega-3 500 EPA ...
Pros
- ✓Enteric coating reliably eliminates fishy burps and aftertaste — the most frequently cited advantage across dozens of reviews
- ✓High potency 500/250 mg EPA/DHA per single softgel reduces the number of capsules needed compared to standard fish oil products
- ✓Molecularly distilled for heavy metal removal; GMP, Non-GMO Project Verified, GOED Omega-3 member, Kosher and Halal certified
- ✓Multiple reviewers report real-world outcomes: reduced joint stiffness, improved focus, skin and hair improvements, and improved blood lipid panels
Cons
- ✗Ethyl ester form rather than the superior triglyceride form — absorption may be meaningfully lower without dietary fat at time of dosing
- ✗Softgels are on the larger side; some users flag swallowing difficulty despite their soft, gel texture
- ✗A minority of reviewers note residual digestive fishy odour (from stomach, not burping) and recommend taking with a fat-containing meal or refrigerating the bottle
- ✗Some iHerb reviews are clearly off-topic or low-information (emoji-only, unrelated product descriptions), slightly reducing the usable review signal
Best For
What does the data say about Life Extension Super O... vs NOW Foods Ultra Omega-...?
Life Extension Super Omega-3 EPA/DHA Fish Oil includes sesame lignans and olive extract to help the 700mg of omega-3s fight inflammation. This earns a 91.0/100 ingredient quality score. NOW Foods Ultra Omega-3 500 EPA / 250 DHA provides a higher 750mg dose but lacks those plant extracts. It uses an enteric coating to stop fishy burps. Both use the ethyl ester form, so take them with a fatty meal to help absorption.
Pick Life Extension Super Omega-3 EPA/DHA Fish Oil for inflammation or cholesterol. It wins on effectiveness (83.0/100) and overall (86.0/100). Pregnant and breastfeeding women should choose this one for the DHA. For a budget, NOW Foods Ultra Omega-3 500 EPA / 250 DHA is the better deal at £19.99. It scores 85.0/100 for value compared to 80.0/100 for Life Extension Super Omega-3 EPA/DHA Fish Oil. It suits adults over 50 for joint health.
Both products use large softgels that might be hard to swallow. If you hate fishy tastes, the enteric coating on the NOW Foods Ultra Omega-3 500 EPA / 250 DHA is a massive plus. Life Extension Super Omega-3 EPA/DHA Fish Oil holds an IFOS 5-star rating for purity.
Life Extension Super Omega-3 is a well-regarded fish oil supplement distinguished from standard options by the addition of sesame lignans and olive fruit extract (hydroxytyrosol), compounds with research-backed synergy with EPA and DHA for extended anti-inflammatory effect.
What are the key differences?
Frequently Asked Questions
Which is better, Life Extension Super Omega-3 EPA/DHA Fish Oil or NOW Foods Ultra Omega-3 500 EPA / 250 DHA? ▼
Is Life Extension Super Omega-3 EPA/DHA Fish Oil worth the price compared to NOW Foods Ultra Omega-3 500 EPA / 250 DHA? ▼
Which has fewer side effects? ▼
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What the Data Says
What is the real cost per dose of omega-3 in the UK?
NOW Foods Ultra Omega-3 costs £0.22/serving — the cheapest effective dose we found across 21 products. That's 750mg EPA+DHA per serving, 90 servings per bottle at £19.99 (value-for-money score: 85/100).
Here's the full price-per-serving breakdown for our top-scoring products:
- NOW Foods Ultra Omega-3: £0.22/serving
- Moller's Omega-3 Liquid Lemon: £0.40/serving
- Life Extension Super Omega-3: £0.42/serving
- WHC UnoCardio 1000: £0.45/serving
- Carlson Elite Omega-3 Gems: £0.67/serving
- Solgar Triple Strength: £0.70/serving
The gap between cheapest and priciest is over 3x per dose. And expensive doesn't mean better — WHC UnoCardio scores highest overall (90/100) at just £0.45/serving, while Solgar scores 79/100 at £0.70. Always divide bottle price by serving count before you compare products.
How much EPA and DHA do you actually need?
250-500mg combined EPA+DHA daily for general health. 1000-2000mg for heart health support. Most health authorities land in that range, and clinical studies typically use 1000mg+.
Our top-scoring omega-3 products hit these targets well:
- WHC UnoCardio 1000 (90/100): 1000mg EPA+DHA — sits right in the clinical sweet spot
- Carlson Elite Omega-3 Gems (87/100): 1600mg total omega-3 (including 800mg EPA + 600mg DHA) — the highest dose in our top 6
- Moller's Omega-3 Liquid (80/100): 1200mg per 5ml teaspoon
- Solgar Triple Strength (79/100): 950mg EPA+DHA
- NOW Foods Ultra Omega-3 (83/100): 750mg EPA+DHA
- Life Extension Super Omega-3 (86/100): 700mg EPA+DHA + sesame lignans
One thing to watch: check the label for the EPA and DHA split, not just "total omega-3." Total omega-3 includes other fatty acids like ALA that aren't as well studied for the same benefits. Most research uses EPA-dominant or balanced EPA/DHA formulas.
Disclaimer: AIScored provides data-driven comparisons based on publicly available reviews. This is not medical advice. Affiliate links may earn us a commission at no extra cost to you.
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