Folate (As Metafolin®) 400µg 50 Tablets vs Liquid B12 2000µg with B-Complex 59ml

Q: Which is better, Folate (As Metafolin®) 400µg 50 Tablets or Liquid B12 2000µg with B-Complex 59ml?

Folate (As Metafolin®) 400µg 50 Tablets scores 86.0/100 while Liquid B12 2000µg with B-Complex 59ml scores 80.0/100 in our analysis. Folate (As Metafolin®) 400µg 50 Tablets is the higher-rated product overall.

Q: Is Folate (As Metafolin®) 400µg 50 Tablets worth the price compared to Liquid B12 2000µg with B-Complex 59ml?

Folate (As Metafolin®) 400µg 50 Tablets scores 68.0/100 for value, while Liquid B12 2000µg with B-Complex 59ml scores 80.0/100. Check our price comparison above for the latest UK prices.

Side-by-side comparison of scores, ingredients, prices and real customer feedback for Folate (As Metafolin®) 400µg 50 Tablets and Liquid B12 2000µg with B-Complex 59ml.

Last verified: 07 Apr 2026 · Based on 62 reviews

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86.0

Quick Answer

Folate (As Metafolin®) 400µg 50 Tablets scores 86.0/100 vs Liquid B12 2000µg with B-Complex 59ml at 80.0/100. Folate (As Metafolin®) 400µg 50 Tablets wins on ingredient quality, side effects, certifications. Liquid B12 2000µg with B-Complex 59ml is stronger on effectiveness and value for money.

How Do the Scores Compare?

Folate (As Metafolin®) 400µ...

Liquid B12 2000µg with B-Co...

	Folate (As Metafolin®) 400µ... Solgar	Liquid B12 2000µg with B-Co... Solgar
Overall Score	86.0	80.0
Effectiveness	88.0/100	90.0/100 Best
Ingredient Quality	93.0/100 Best	70.0/100
Value for Money	68.0/100	80.0/100 Best
Side Effects	95.0/100 Best	80.0/100
Certifications	76.0/100 Best	40.0/100
Best Price	£9.20 Holland & Barrett → Cheapest	£15.60 Holland & Barrett →
Form	Tablets	liquid
Dose	None	None
Third-Party Tested	✗ No	✗ No
Reviews Analysed	58	4

Folate (As Metafolin®) 400µg 50 Tablets

Pros

✓Uses Metafolin® (L-5-methyltetrahydrofolate), the bioactive form directly usable by the body — superior absorption vs. synthetic folic acid
✓Highly effective for MTHFR mutation carriers who cannot convert regular folic acid
✓Multiple reviewers report confirmed improvements in blood folate levels via lab testing
✓Small, easy-to-swallow tablets with neutral taste and no reported digestive side effects

Cons

✗Small pack size — 50 tablets is only ~7 weeks' supply at the standard one-per-day dose
✗Not third-party tested per product specs, limiting independent purity verification
✗One Amazon reviewer reported receiving 46 tablets instead of 50 (possible quality control lapse)
✗Several iHerb reviews appear to describe the 1000mcg/120-tablet variant rather than this 400µg/50-tablet product, slightly muddying the review signal

Best For

Women planning pregnancy or currently pregnant MTHFR mutation carriers who cannot efficiently convert synthetic folic acid People with diagnosed folate deficiency Those seeking a clean, minimal-additive B-vitamin supplement Anyone wanting a well-trusted, established supplement brand

Holland & Barrett £9.20 Amazon UK £16.94

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Liquid B12 2000µg with B-Complex 59ml

Pros

✓Consistently excellent user satisfaction (4/4 reviews at 5 stars) with reported improvement in energy and B12 levels
✓High bioavailability sublingual format may absorb better than tablets for B12 absorption
✓Generous 2000µg B12 dose plus complete B-complex for synergistic metabolic support
✓Suitable for vegans and vegetarians (particularly important given B12 is animal-derived)

Cons

✗No third-party testing or quality verification certification visible
✗Contains palm kernel oil (glycerin source) which may concern environmentally-conscious consumers
✗Cyanocobalamin form is synthetic; some prefer methylcobalamin as more bioavailable
✗Potassium sorbate preservative and artificial flavoring agents may deter some natural-focused buyers

Best For

Vegans and vegetarians (critical B12 source) People with B12 deficiency or absorption issues Those who struggle to swallow tablets or capsules Individuals seeking high-potency B12 with metabolic support People experiencing fatigue or low energy

Holland & Barrett £15.60

View full review →

What does the data say about Folate (As Metafolin®)... vs Liquid B12 2000µg with...?

Folate 400µg as Metafolin 50 Tablets scores 86.0/100 overall while Liquid B12 2000µg with B-Complex 59ml scores 80.0/100. The first uses the bioactive L-5-methyltetrahydrofolate form at 400µg in tablet shape. The second delivers 2000µg of B12 in liquid format plus a full B-complex. One offers direct body-ready folate. The other provides high dose B12 through sublingual drops for easier uptake.

People planning pregnancy or with MTHFR mutation should pick Folate 400µg as Metafolin because it scores 93.0/100 on ingredient quality and 88.0/100 on effectiveness. Those with B12 deficiency or absorption problems and anyone who dislikes swallowing tablets should choose Liquid B12 2000µg with B-Complex. It wins on effectiveness at 90.0/100 and value at 80.0/100 compared with 68.0/100 for the folate product. Budget matters too since the folate costs £9.20 for 50 tablets while the liquid costs £15.60 for 59ml.

Practical points include the small 50-tablet pack that lasts roughly seven weeks at one per day. The liquid version gives consistent five-star feedback on energy improvements yet contains palm kernel oil which some avoid. Both come from Solgar in the B Vitamins category.

Folate (As Metafolin®) 400µg 50 Tablets Winner 86.0/100

Solgar's Folate as Metafolin® 400µg is a premium-grade folate supplement using L-methylfolate, the bioidentical, body-ready form of vitamin B9 that bypasses the need for hepatic conversion.

Effectiveness

Folate (As Metaf..

88.0/100

Liquid B12 2000µ..

90.0/100

Ingredient Quality

Folate (As Metaf..

93.0/100

Liquid B12 2000µ..

70.0/100

Value for Money

Folate (As Metaf..

68.0/100

Liquid B12 2000µ..

80.0/100

Side Effects

Folate (As Metaf..

95.0/100

Liquid B12 2000µ..

80.0/100

Certifications

Folate (As Metaf..

76.0/100

Liquid B12 2000µ..

40.0/100

What are the key differences?

Folate (As Metafolin®) .. is best for: Women planning pregnancy or currently pregnant, MTHFR mutation carriers who cannot efficiently convert synthetic folic acid

Liquid B12 2000µg with .. is best for: Vegans and vegetarians (critical B12 source), People with B12 deficiency or absorption issues

Frequently Asked Questions

Which is better, Folate (As Metafolin®) 400µg 50 Tablets or Liquid B12 2000µg with B-Complex 59ml? ▼

Folate (As Metafolin®) 400µg 50 Tablets scores 86.0/100 overall while Liquid B12 2000µg with B-Complex 59ml scores 80.0/100. Folate (As Metafolin®) 400µg 50 Tablets comes out ahead, scoring higher on effectiveness (88.0 vs 90.0). Folate (As Metafolin®) 400µg 5 is best suited for Women planning pregnancy or currently pregnant and MTHFR mutation carriers who cannot efficiently convert synthetic folic acid. Liquid B12 2000µg with B-Compl is better for Vegans and vegetarians (critical B12 source) and People with B12 deficiency or absorption issues.

Is Folate (As Metafolin®) 400µg 50 Tablets worth the price compared to Liquid B12 2000µg with B-Complex 59ml? ▼

Folate (As Metafolin®) 400µg 50 Tablets costs £9.20 while Liquid B12 2000µg with B-Complex 59ml is £15.60. For value, Folate (As Metafolin®) 400µg 50 Tablets scores 68.0/100 vs Liquid B12 2000µg with B-Complex 59ml's 80.0/100. Liquid B12 2000µg with B-Complex 59ml delivers better value relative to its quality. Note that Folate (As Metafolin comes as tablets while Liquid B12 2000µg wi is liquid, which may affect your preference.

Which has fewer side effects? ▼

Folate (As Metafolin®) 400µg 50 Tablets scores 95.0/100 for side effects (higher means fewer reported issues) while Liquid B12 2000µg with B-Complex 59ml scores 80.0/100. Reviewers report fewer side effects with Folate (As Metafolin®) 400µg 50 Tablets. For certification and testing, Folate (As Metafolin scores 76.0/100 vs Liquid B12 2000µg wi's 40.0/100. Always consult a healthcare professional before starting any supplement.